Fig. 5From: BTB and CNC homology 1 (Bach1) induces lung cancer stem cell phenotypes by stimulating CD44 expressionRelationship of MAPK signaling and lung CSCs. Microarray analysis was applied to screen the mRNAs which can be regulated by Bach1. A Volcano plot of the data showing altered gene expression in A549 CSCs transfected with or without LV-shBach1. B, C KEGG pathway analysis revealed the signaling pathways potentially involved in Bach1-mediated functions. D Top 20 genes involved in the MAPK signaling pathway. E, F p-p38, p-AKT1, c-Fos and c-Jun protein expressionBack to article page