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Fig. 2 | Respiratory Research

Fig. 2

From: HuR drives lung fibroblast differentiation but not metabolic reprogramming in response to TGF-β and hypoxia

Fig. 2

Alterations in components of the glycolytic pathway. a There was a significant increase in LDHA mRNA levels following treatment with hypoxia with TGF-β1. b There was a modest increase in HKII mRNA after treatment with hypoxia and TGF-β1. Values are represented as the mean ± SEM (n = 3–4 independent experiments utilizing cells from 3 separate subjects). Means are expressed as fold change from the control (24 h- normoxia; *p < 0.05 compared to control). c There was a significant increase in LDHA protein in response to TGF-β together with hypoxia compared to normoxia. d HKII protein did not significantly changes with exposures

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