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Fig. 11 | Respiratory Research

Fig. 11

From: HuR drives lung fibroblast differentiation but not metabolic reprogramming in response to TGF-β and hypoxia

Fig. 11

A schematic representation of the role of HuR in response to TGF-β1 and hypoxia. In response to TGF-β1 and 1% O2 (hypoxia), HuR translocates to the cytoplasm. HuR is crucial in the process of fibroblast differentiation and collagen production. Hypoxia greatly reduced TGF-β1-induced fibroblast differentiation and lactate production through an unknown mechanism

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Respiratory Research

ISSN: 1465-993X

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