Absolutely non-awake ECMO (n = 31) | Tried awake ECMO (n = 8) | Awake ECMO (n = 25) | p | |
---|---|---|---|---|
Age, years | 54 (49–59) | 59.5 (54.5–62.8) | 59 (52.5–63) | 0.148 |
Male, sex | 15 (48.4) | 6 (75) | 20 (80) | 0.043 |
BMI, kg/m2 | 21.5 (18.5–25.1) | 22.4 (20.7–26.0) | 19.3 (16.8–23.2) | 0.173 |
Primary lung disease | 0.404 | |||
IPF | 13 (41.9) | 4 (50) | 14 (56) | |
AIP/ARDS | 4 (12.9) | 0 (0) | 0 (0) | |
CTD-related ILD | 4 (12.9) | 3 (37.5) | 4 (16) | |
BO after PBSCT | 1 (3.2) | 0 (0) | 2 (8) | |
Other | 9 (29) | 1 (12.5) | 5 (20) | |
Hypertension | 9 (29) | 1 (12.5) | 5 (20) | 0.649 |
Diabetes mellitus | 9 (31) | 4 (50) | 6 (24) | 0.381 |
Pulmonary hypertension | 17 (54.8) | 5 (62.5) | 12 (48) | 0.829 |
TTE parameters before LTx | ||||
EF, % | 61 (56–66) | 67 (58.3–75.3) | 62 (55–68) | 0.286 |
E/E’ | 11 (8–12) | 9 (6.9–12.5) | 10 (8.2–12) | 0.725 |
RVSP, mmHg | 48 (30.8–61) | 58 (32.3–69.3) | 49 (37.5–53) | 0.493 |
APACHE II score | 21 (17–28) | 26 (21.5–28.8) | 18 (13–19) | 0.003 |
ECMO blood flow, mL | 3170 (2750–3550) | 3270 (3100–3560) | 3010 (2525–3575) | 0.443 |
ECMO duration, days | 10 (4–19) | 17.5 (9.5–26.5) | 13 (8–17) | 0.277 |
Ventilator free days | 0 (0–20) | 5 (0–17) | 24 (17–26) | < 0.001 |
Three-month mortality | 7 (22.6) | 2 (25) | 1 (4) | 0.085 |
Six-month mortality | 12 (38.7) | 3 (37.5) | 3 (12) | 0.049 |
One-year mortality | 16 (51.6) | 5 (62.5) | 6 (24) | 0.053 |
Ability to gait after LTx | 18 (58.1) | 5 (62.5) | 23 (92) | 0.009 |
Time to gaiting, days | 27 (18–33) | 28 (21–47) | 17 (10–29) | 0.089 |
ICU length of stay, days | 18 (11–37) | 16 (9.8–31.8) | 6 (4–8.5) | < 0.001 |
Hospital length of stay, days | 51 (38–92) | 85 (58.8–173.8) | 36 (24–91) | 0.043 |
Six-month FVC, % (11/3/18)* | 61 (49–65) | 70 (68.5–70.5) | 70 (59.5–78.5) | 0.045 |
Six-month FEV1, % (11/3/18)* | 56 (40–64) | 72 (72–72.5) | 77.5 (69–96.5) | 0.011 |
One-year FVC, % (12/3/18)* | 61 (53–68) | 65 (63.5–83.5) | 71 (62.8–79.3) | 0.056 |
One-year FEV1, % (12/3/18)* | 57 (45.3–67.8) | 70 (63–92.5) | 75 (61.5–96.8) | 0.017 |