Table 2 Comparison between non-awake ECMO and awake ECMO patients after propensity score matching of the APACHE II score and ECMO duration
Non-awake ECMO (n = 25) | Awake ECMO (n = 25) | p | |
|---|---|---|---|
Age, years | 54 (48.5–59) | 59 (52.5–63) | 0.084 |
Male, sex | 11 (44) | 20 (80) | 0.009 |
BMI, kg/m2 | 21.3 (19.1–25.2) | 19.3 (16.8–23.2) | 0.16 |
Primary lung disease | 0.059 | ||
IPF | 7 (28) | 14 (56) | |
AIP/ARDS | 3 (12) | 0 (0) | |
CTD-related ILD | 6 (24) | 4 (16) | |
BO after PBSCT | 1 (4) | 2 (8) | |
Other | 7 (32) | 5 (20) | |
Hypertension | 5 (20) | 5 (20) | 1 |
Diabetes mellitus | 8 (32) | 6 (24) | 0.529 |
Pulmonary hypertension | 13 (52) | 12 (48) | 0.777 |
TTE parameters before LTx | |||
EF, % | 61 (56–69) | 62 (55–68) | 0.808 |
E/E’ | 10 (8–11.5) | 10 (8.2–12) | 0.856 |
RVSP, mmHg | 45 (27.9–54) | 49 (37.5–53) | 0.453 |
APACHE II score, | 20 (14–22) | 18 (13–19) | 0.117 |
ECMO blood flow, mL | 3140 (2940–3400) | 3010 (2525–3575) | 0.479 |
ECMO duration, days | 11 (8–19.5) | 13 (8–17) | 0.904 |
Ventilator free days | 0 (0–20) | 24 (17–26) | < 0.001 |
Ability to gait after LTx | 14 (56) | 23 (92) | 0.004 |
Time to gaiting, days | 22 (10–33) | 17 (10–29) | 0.248 |
Three-month mortality | 6 (24) | 1 (4) | 0.098 |
Six-month mortality | 8 (32) | 3 (12) | 0.088 |
One-year mortality | 12 (48) | 6 (24) | 0.077 |
ICU length of stay, days | 13 (6.5–24.5) | 6 (4–8.5) | 0.001 |
Hospital length of stay, days | 51 (36–90) | 36 (24–91) | 0.327 |
Six-month FVC, % (10/18)* | 61.5 (50.5–66.3) | 70 (59.5–78.5) | 0.031 |
Six-month FEV1, % (10/18)* | 58 (41.5–66) | 77.5 (69–96.5) | 0.001 |
One-year FVC, % (12/18)* | 60.5 (53–65) | 71 (62.8–79.3) | 0.009 |
One-year FEV1, % (12/18)* | 56.5 (45.3–60.5) | 75 (61.5–96.8) | < 0.001 |