Fig. 1

The pathological changes of mice with tracheal injury were improved by FA. A C57BL/J male mice were treated intraperitoneally with normal saline or FA (100 mg/kg) 12 h before and 12 h after intratracheal administration of LPS (5 mg/kg), and then extracted tracheas were applied to hematoxylin and eosin (HE) staining (original objective × 400). The black arrow indicates the abnormal ciliated columnar epithelia, and the line segment represents the height of trachea epithelium. B Five points were randomly selected to measure the height of tracheal epithelium in each group. C Number of tracheal epithelial cells per area. ***P < 0.001, compared with Control group, ^&&&P < 0.001, compared with LPS group, n = 5