Skip to main content

Table 2 Haemodynamic parameters and risk factors for the whole group and according to the HRCT pattern

From: Predictive value of chest HRCT for survival in idiopathic pulmonary arterial hypertension

 

All patients

cGGO pattern

pGGO pattern

Normal pattern

p value*

N

Median (IQR) or N (%)

N

Median (IQR) or N (%)

N

Median (IQR) or N (%)

N

Median (IQR) or N (%)

RAPm [mmHg]

107

8 (5–11)

24

10 (8–13)

26

7 (4–10)

57

8.0 (5.0–10.0)

0.024

RAPm risk group:

107

 

24

 

26

 

57

 

0.055

 Low

 

51 (48)

 

6 (25)

 

17 (65)

 

28 (49)

 

 Intermediate

 

44 (41)

 

13 (54)

 

8 (31)

 

23 (40)

 

 High

 

12 (11)

 

5 (21)

 

1 (4)

 

6 (11)

 

PAPs [mmHg]

108

83 (69–97)

24

86 (69,5–102.5)

26

85 (73–95)

58

79.5 (67.0–93.0)

0.24

PAPd [mmHg]

108

39.5 (31–50)

24

43.5 (33.5–54.0)

26

40.5 (29–49)

58

37.5 (29.0–47.0)

0.15

PAPm [mmHg]

108

55 (46.5–67.5)

24

61.5 (48.0–73.5)

26

58.5 (46–67)

58

54.0 (44.0–64.0)

0.12

CO [l/min]

108

4.4 (3.7–5.2)

24

4.2 (3.6–5.1)

26

4.2 (3.7–4.6)

58

4.7 (3.7–5.3)

0.20

CI [l/min/m2]

108

2.5 (2.2–3.0)

24

2.5 (2.3–3.1)

26

2.6 (2.2–2.8)

58

2.5 (2.2–3.1)

0.90

CI risk group:

108

 

24

 

26

 

58

 

0.56

 Low

 

54 (50)

 

10 (42)

 

16 (62)

 

28 (48)

 

 Intermediate

 

42 (39)

 

12 (50)

 

7 (27)

8

23 (40)

 

 High

 

12 (11)

 

2 (8)

 

3 (11)

 

7 (12)

 

Svo2 [%]

108

61 (53.5–69.0)

24

63 (55.5–70.0)

26

61.5 (53–69)

58

59.0 (54.0–68.0)

0.68

Svo2 risk group:

108

 

24

 

26

 

58

 

0.32

 Low

 

36 (33)

 

9 (38)

 

10 (39)

 

17 (29)

 

 Intermediate

 

23 (21)

 

8 (33)

 

4 (15)

 

11 (19)

 

 High

 

49 (45)

 

7 (29)

 

12 (46)

 

30 (52)

 

PVR [Wood units]

108

10.3 (8.1–14.4)

24

12.6 (8.8–16.8)

26

9.9 (8.4–15.2)

58

9.8 (7.5–13.2)

0.15

Responder

102

22 (22)

23

5 (22)

23

7 (30)

56

10 (18)

0.47

Risk group:

110

 

24

 

26

 

60

 

0.57

 Low

 

30 (27)

 

5 (21)

 

8 (31)

 

17 (28)

 

 Intermediate

 

66 (60)

 

15 (62)

 

17 (65)

 

34 (57)

 

 High

 

14 (13)

 

4 (17)

 

1 (4)

 

9 (15)

 

Number of low-risk factors

110

2.0 (1.0–4.0)

24

2.0 (1.0–3.0)

26

3.0 (2.0–4.0)

60

2.0 (0.0–3.5)

0.072

Number of intermediate/high-risk factors

110

3.0 (2.0–5.0)

24

4.0 (3.0–5.0)

26

3.0 (1.0–4.0)

60

4.0 (2.0–5.0)

0.25

  1. Bold values denote statistical significance at the p < 0.05 level
  2. cGGO, centrilobular ground glass opacifications; pGGO, panlobular ground glass opacification; IQR, interquartile range; RAPm, mean right atrial pressure; PAPs/d/m, systolic, diastolic and mean pulmonary artery pressures; CO, cardiac output; CI, cardiac index; SvO2, mixed venous blood oxygen saturation; PVR, pulmonary vascular resistance. *For comparison between three HRCT patterns