Skip to main content

Table 2 Haemodynamic parameters and risk factors for the whole group and according to the HRCT pattern

From: Predictive value of chest HRCT for survival in idiopathic pulmonary arterial hypertension

  All patients cGGO pattern pGGO pattern Normal pattern p value*
N Median (IQR) or N (%) N Median (IQR) or N (%) N Median (IQR) or N (%) N Median (IQR) or N (%)
RAPm [mmHg] 107 8 (5–11) 24 10 (8–13) 26 7 (4–10) 57 8.0 (5.0–10.0) 0.024
RAPm risk group: 107   24   26   57   0.055
 Low   51 (48)   6 (25)   17 (65)   28 (49)  
 Intermediate   44 (41)   13 (54)   8 (31)   23 (40)  
 High   12 (11)   5 (21)   1 (4)   6 (11)  
PAPs [mmHg] 108 83 (69–97) 24 86 (69,5–102.5) 26 85 (73–95) 58 79.5 (67.0–93.0) 0.24
PAPd [mmHg] 108 39.5 (31–50) 24 43.5 (33.5–54.0) 26 40.5 (29–49) 58 37.5 (29.0–47.0) 0.15
PAPm [mmHg] 108 55 (46.5–67.5) 24 61.5 (48.0–73.5) 26 58.5 (46–67) 58 54.0 (44.0–64.0) 0.12
CO [l/min] 108 4.4 (3.7–5.2) 24 4.2 (3.6–5.1) 26 4.2 (3.7–4.6) 58 4.7 (3.7–5.3) 0.20
CI [l/min/m2] 108 2.5 (2.2–3.0) 24 2.5 (2.3–3.1) 26 2.6 (2.2–2.8) 58 2.5 (2.2–3.1) 0.90
CI risk group: 108   24   26   58   0.56
 Low   54 (50)   10 (42)   16 (62)   28 (48)  
 Intermediate   42 (39)   12 (50)   7 (27) 8 23 (40)  
 High   12 (11)   2 (8)   3 (11)   7 (12)  
Svo2 [%] 108 61 (53.5–69.0) 24 63 (55.5–70.0) 26 61.5 (53–69) 58 59.0 (54.0–68.0) 0.68
Svo2 risk group: 108   24   26   58   0.32
 Low   36 (33)   9 (38)   10 (39)   17 (29)  
 Intermediate   23 (21)   8 (33)   4 (15)   11 (19)  
 High   49 (45)   7 (29)   12 (46)   30 (52)  
PVR [Wood units] 108 10.3 (8.1–14.4) 24 12.6 (8.8–16.8) 26 9.9 (8.4–15.2) 58 9.8 (7.5–13.2) 0.15
Responder 102 22 (22) 23 5 (22) 23 7 (30) 56 10 (18) 0.47
Risk group: 110   24   26   60   0.57
 Low   30 (27)   5 (21)   8 (31)   17 (28)  
 Intermediate   66 (60)   15 (62)   17 (65)   34 (57)  
 High   14 (13)   4 (17)   1 (4)   9 (15)  
Number of low-risk factors 110 2.0 (1.0–4.0) 24 2.0 (1.0–3.0) 26 3.0 (2.0–4.0) 60 2.0 (0.0–3.5) 0.072
Number of intermediate/high-risk factors 110 3.0 (2.0–5.0) 24 4.0 (3.0–5.0) 26 3.0 (1.0–4.0) 60 4.0 (2.0–5.0) 0.25
  1. Bold values denote statistical significance at the p < 0.05 level
  2. cGGO, centrilobular ground glass opacifications; pGGO, panlobular ground glass opacification; IQR, interquartile range; RAPm, mean right atrial pressure; PAPs/d/m, systolic, diastolic and mean pulmonary artery pressures; CO, cardiac output; CI, cardiac index; SvO2, mixed venous blood oxygen saturation; PVR, pulmonary vascular resistance. *For comparison between three HRCT patterns