Table 1 Demographic, functional and biochemical parameters for the whole group and according to the HRCT pattern
From: Predictive value of chest HRCT for survival in idiopathic pulmonary arterial hypertension
All patients | cGGO pattern | pGGO pattern | Normal pattern | p value* | |||||
|---|---|---|---|---|---|---|---|---|---|
N | Median (IQR) or N (%) | N | Median (IQR) or N (%) | N | Median (IQR) or N (%) | N | Median (IQR) or N (%) | ||
Age [years] | 110 | 44.3 (30.0–56.6) | 24 | 32.1 (24.3–49.0) | 26 | 44 (27–49.6) | 60 | 46.8 (37.6–59.0) | 0.064 |
Age < 40 years | 110 | 44 (40) | 24 | 15 (63) | 26 | 12 (46) | 60 | 17 (28) | 0.012 |
Sex female:male | 110 | 80:30 (73:27) | 24 | 20:4 (83:17) | 26 | 23:3 (88:12) | 60 | 37:23 (62:38) | 0.016 |
Ever-smokers | 106 | 41 (39) | 21 | 9 (43) | 26 | 5 (19) | 59 | 27 (46) | 0.062 |
Positive history of haemoptysis | 108 | 18 (16) | 24 | 7 (29) | 26 | 6 (23) | 58 | 5 (9) | 0.046 |
PFO | 93 | 29 (31) | 22 | 7 (32) | 20 | 8 (40) | 59 | 14 (27) | 0.59 |
WHO FC: | 107 | 24 | 26 | 57 | 0.14 | ||||
1 | 0 | 0 | 0 | 0 | |||||
2 | 57 (53) | 14 (58) | 17 (65) | 26 (46) | |||||
3 | 44 (41) | 7 (29) | 8 (31) | 29 (51) | |||||
4 | 6 (6) | 3 (13) | 1 (4) | 2 (4) | |||||
DLCO [%pred] | 84 | 66.8 (52.8–76.5) | 15 | 58.7 (33.4–71.6) | 21 | 70.6 (60.4–73.6) | 48 | 66.7 (39.0–83.1) | 0.27 |
6MWD [m] | 105 | 396 (318–474) | 21 | 436 (380–484) | 26 | 415.5 (380–484) | 58 | 379.5 (298.0–450.0) | 0.06 |
6MWD risk group: | 105 | 21 | 26 | 58 | 0.34 | ||||
Low | 37 (35) | 10 (48) | 11 (42) | 16 (28) | |||||
Intermediate | 63 (60) | 11 (52) | 14 (54) | 38 (66) | |||||
High | 5 (5) | 0 (0) | 1 (4) | 4 (7) | |||||
SpO2 [%] | 105 | 86 (92–97) | 21 | 96 (92–97) | 26 | 96.5 (93–98) | 58 | 95.0 (91.0–97.0) | 0.20 |
6MWT ΔSpO2 | 102 | 5 (1–8) | 21 | 5 (3–9) | 26 | 4.5 (2–8) | 55 | 4.0 (0.0–9.0) | 0.50 |
NT-proBNP [pg/ml] | 83 | 1079 (332–2592) | 22 | 1619.5 (422.9–4331.0) | 21 | 825 (219.9–1610.0) | 40 | 1121.0 (360.0–2599.0) | 0.30 |
NT-proBNP risk group: | 83 | 22 | 21 | 40 | 0.54 | ||||
Low | 18 (22) | 4 (18) | 6 (28.5) | 8 (20) | |||||
Intermediate | 29 (35) | 6 (27) | 9 (43) | 14 (35) | |||||
High | 36 (43) | 12 (55) | 6 (28.5) | 18 (45) | |||||