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Table 2 Analyses of prognostic factors in patients with IIPs (Cox proportional hazards model)

From: Radiological pleuroparenchymal fibroelastosis-like lesion in idiopathic interstitial pneumonias

Variable

Univariate

Multivariate

HR

95% CI

p value

HR

95% CI

p value

Age (years)

1.05

1.03–1.08

 < 0.0001

1.05

1.02–1.08

0.0001

Sex (male)

1.84

1.21–2.89

0.0036

1.32

0.82–2.20

0.2593

IPF diagnosis

2.47

1.70–3.65

 < 0.0001

2.55

1.68–3.94

 < 0.0001

PaO2 (mmHg)

1.00

0.99–1.01

0.5115

   

PaCO2 (mmHg)

1.01

0.99–1.01

0.1163

   

KL-6 (U/mL)

1.00

0.999–1.000

0.7180

   

%FVC, %

0.99

0.977–0.996

0.0043

0.98

0.97–0.99

 < 0.0001

%DLCO, %

0.99

0.979–0.998

0.0203

   

UIP pattern

2.71

1.66–4.25

0.0002

   

PPFE-like lesion

2.32

1.56–3.38

 < 0.0001

2.54

1.64–3.89

 < 0.0001

Emphysema

1.61

1.10–2.34

0.0141

1.99

1.29–3.09

0.0021

Honeycombing

2.99

1.86–4.63

 < 0.0001

1.50

0.90–2.42

0.1177

  1. IPF idiopathic pulmonary fibrosis; PaO2 arterial oxygen tension; PaCO2 arterial carbon dioxide tension; KL-6 Krebs von den Lungen-6; FVC forced vital capacity; DLCO diffusing capacity for carbon monoxide; UIP usual interstitial pneumonia; PPFE pleuroparenchymal fibroelastosis; HR hazard ratio
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Respiratory Research

ISSN: 1465-993X

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