Fig. 1
From: α1-Antitrypsin attenuates acute rejection of orthotopic murine lung allografts
Study protocol. Donor lungs were harvested from BALB/CJ mice. Alpha1-antitrypsin (AAT) was administrated subcutaneously to the recipient before the transplantation. A harvested lung was transplanted into a C57BL/6 mouse orthotopically. After the transplantation, the second dose of AAT was immediately injected intraperitoneally. Control mice received no AAT, but the same volume of saline vehicle. The transplanted mice received analgesic and antibiotic, but no immune suppression. Three days after the transplantation, the mice were sacrificed, and whole blood and lung lobes were harvested