Fig. 11
Effect of pretreatment with the tetrodotoxin (TTX)-sensitive channel blocker, TTX, on PGE2-enhanced citric acid-induced cough. Pretreatment of guinea pigs with 15 μl of TTX (0.015 µg/ml; n = 7 and 0.1 µg/ml; n = 5, i.c.v.) did not affect the PGE2-enhanced citric acid-induced cough response compared to vehicle (n = 7). Data are plotted as a scatter graph A and a bar chart B showing mean cough ± SEM