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Table 1 Patients hospitalized with pulmonary embolism in France: Summary statistics (2017–2020)

From: Impact of COVID-19 and lockdowns on pulmonary embolism in hospitalized patients in France: a nationwide study

 

2017

2018

2019

2020

p-value* (comparison of the 4 years)

2020 COVID-19 from 1st March to 31st December

p-value** (comparison to 2019)

2020 non-COVID-19

from 1st March to 31st December

p-value** (comparison to 2019)

Hospitalized patients with PE (n)

68 520

70 201

71 167

82 448

 

9 693

 

59 848

 

Rate of change (%)

 

2.5%

1.4%

15.8%

     

Hospitalized patients (n)

10 297 403

10 417 988

10 527 664

9 538 270

 

259 482

 

7 717 759

 

PE frequency among hospitalized patients (%)

0.67% [0.665–0.675]

0.67% [0.665–0.675]

0.68% [0.675–0.685]

0.86% [0.854–0.866]

 

3.74% [3.67–3.81]

 

0.77% [0.76–0.78]

 

Age (years)

         

Mean ± sd

70 ± 16

70 ± 16

69 ± 16

69 ± 16

 < 0.01

69 ± 16

 < 0.01

69 ± 17

0.0033

Median [Q1-Q3]

72 [60–82]

71 [60–82]

72 [60–82]

71 [59–82]

0.0007

70 [59–81]

 < 0.01

72 [59–82]

0.5491

Min–Max

18–109

18–105

18–109

18–108

 

18–104

 

18–108

 

Female frequency in hospitalized PE

51.6% [51.2–52.0]

52.3% [51.9–52.7]

51.6% [51.2–52.0]

49.8% [49.5–50.1]

 < 0.01

40.6% [39.6–41.6]

 < 0.01

50.8% [50.4–51.2]

0.0023

Obesity frequency in hospitalized PE

8.6% [8.4–8.8]

8.7% [8.5–8.9]

8.8% [8.6–9.0]

9.5% [9.3–9.7]

 < 0.01

13.1% [12.4–13.8]

 < 0.01

9.0% [8.8–9.2]

0.1656

Cancer frequency in hospitalized PE

23.1% [22.8–23.4]

22.7% [22.4–23.0]

23.2% [22.4–23.0]

21.5% [21.2–21.8]

 < 0.01

10.2% [9 .6–10.8]

 < 0.01

22.9% [22.6–23.2]

0.1127

Surgery frequency in the 2 months before hospitalization with PE

NA

NA

5.2% [5.0–5.4]

4.6% [4.5–4.7]

NA

2.7% [2.4–3.0]

 < 0.01

5.2% [5.0–5.4]

0.9707

Initial*** PE in hospitalized PE

85.2% [84.9–85.5]

85.5% [85.2–85.8]

82.0% [81.7–82.3]

81.8% [81.5–82.1]

 < 0.01

75.5% [74.6–76.4]

 < 0.01

82.3% [82.0–82.6]

0.1546

ICU frequency in hospitalized PE

25.3% [25.0–25.6]

25.0% [24.7–25.3]

25.2% [24.9–25.5]

25.8% [25.5–26.1]

0.0043

34.3% [33.4–35.2]

 < 0.01

24.8% [24.5–25.1]

0.0960

Death frequency among hospitalized PE

9.2% [9.0–9.4]

9.0% [8.8–9.2]

9.1% [8.9–9.3]

10.3% [10.1–10.5]

 < 0.01

19.3% [18.5–20.1]

 < 0.01

9.1% [8.9–9.3]

0.8510

  1. PE: pulmonary embolism, SD Standard deviation, ICU intensive care unit, NA not applicable
  2. * Kruskal–Wallis test and Brown-Mood test for comparison of age and Chi-2 test for other variables
  3. **Mann–Whitney test and Brown-Mood test for comparison of age and Chi-2 test for other variables
  4. *** PE diagnosed in the first unit of hospitalization