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Table 1 Patients hospitalized with pulmonary embolism in France: Summary statistics (2017–2020)

From: Impact of COVID-19 and lockdowns on pulmonary embolism in hospitalized patients in France: a nationwide study

  2017 2018 2019 2020 p-value* (comparison of the 4 years) 2020 COVID-19 from 1st March to 31st December p-value** (comparison to 2019) 2020 non-COVID-19
from 1st March to 31st December
p-value** (comparison to 2019)
Hospitalized patients with PE (n) 68 520 70 201 71 167 82 448   9 693   59 848  
Rate of change (%)   2.5% 1.4% 15.8%      
Hospitalized patients (n) 10 297 403 10 417 988 10 527 664 9 538 270   259 482   7 717 759  
PE frequency among hospitalized patients (%) 0.67% [0.665–0.675] 0.67% [0.665–0.675] 0.68% [0.675–0.685] 0.86% [0.854–0.866]   3.74% [3.67–3.81]   0.77% [0.76–0.78]  
Age (years)          
Mean ± sd 70 ± 16 70 ± 16 69 ± 16 69 ± 16  < 0.01 69 ± 16  < 0.01 69 ± 17 0.0033
Median [Q1-Q3] 72 [60–82] 71 [60–82] 72 [60–82] 71 [59–82] 0.0007 70 [59–81]  < 0.01 72 [59–82] 0.5491
Min–Max 18–109 18–105 18–109 18–108   18–104   18–108  
Female frequency in hospitalized PE 51.6% [51.2–52.0] 52.3% [51.9–52.7] 51.6% [51.2–52.0] 49.8% [49.5–50.1]  < 0.01 40.6% [39.6–41.6]  < 0.01 50.8% [50.4–51.2] 0.0023
Obesity frequency in hospitalized PE 8.6% [8.4–8.8] 8.7% [8.5–8.9] 8.8% [8.6–9.0] 9.5% [9.3–9.7]  < 0.01 13.1% [12.4–13.8]  < 0.01 9.0% [8.8–9.2] 0.1656
Cancer frequency in hospitalized PE 23.1% [22.8–23.4] 22.7% [22.4–23.0] 23.2% [22.4–23.0] 21.5% [21.2–21.8]  < 0.01 10.2% [9 .6–10.8]  < 0.01 22.9% [22.6–23.2] 0.1127
Surgery frequency in the 2 months before hospitalization with PE NA NA 5.2% [5.0–5.4] 4.6% [4.5–4.7] NA 2.7% [2.4–3.0]  < 0.01 5.2% [5.0–5.4] 0.9707
Initial*** PE in hospitalized PE 85.2% [84.9–85.5] 85.5% [85.2–85.8] 82.0% [81.7–82.3] 81.8% [81.5–82.1]  < 0.01 75.5% [74.6–76.4]  < 0.01 82.3% [82.0–82.6] 0.1546
ICU frequency in hospitalized PE 25.3% [25.0–25.6] 25.0% [24.7–25.3] 25.2% [24.9–25.5] 25.8% [25.5–26.1] 0.0043 34.3% [33.4–35.2]  < 0.01 24.8% [24.5–25.1] 0.0960
Death frequency among hospitalized PE 9.2% [9.0–9.4] 9.0% [8.8–9.2] 9.1% [8.9–9.3] 10.3% [10.1–10.5]  < 0.01 19.3% [18.5–20.1]  < 0.01 9.1% [8.9–9.3] 0.8510
  1. PE: pulmonary embolism, SD Standard deviation, ICU intensive care unit, NA not applicable
  2. * Kruskal–Wallis test and Brown-Mood test for comparison of age and Chi-2 test for other variables
  3. **Mann–Whitney test and Brown-Mood test for comparison of age and Chi-2 test for other variables
  4. *** PE diagnosed in the first unit of hospitalization