Fig. 6

FERMT3 regulates CSE-induced EMT via Wnt/β-Catenin signaling. a β-catenin, p-β-catenin, GSK-3β and p-GSK-3β protein expression in A549 cells treated by CSE in a series of concentrations CSE for 24 h. n = 3 per group. *P < 0.05, **P < 0.01, compared with Control. b β-catenin, p-β-catenin, GSK-3β and p-GSK-3β protein expression in A549 cells transfected with control vector or FERMT3 vector then treated by 3% CSE for 24 h. *P < 0.01, **P < 0.01, compared with control vector; ^#P < 0.05, ^##P < 0.01, compared with control vector + 3% CSE. n = 3 per group. c β-catenin, p-β-catenin and Snail protein expression in A549 cells were transfected with control vector or FERMT3 vector, treated with 3% CSE for 24 h, and then treated with activator LiCl (20 mM) for 24 h. *P < 0.01, **P < 0.01, compared with control vector. n = 3 per group