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Table 4 Comparison of complications between the PF-ILD and non-PF-ILD groups among patients with fibrosing ILD

From: Progressive fibrosing interstitial lung disease: prevalence and clinical outcome

 

Total

PF-ILD

Non-PF-ILD

P-value

Number of patients

396

135

261

 

Follow-up duration, months

68.9 ± 32.5

59.9 ± 28.4

73.5 ± 33.5

 < 0.001

Unexpected respiratory hospitalisation

120 (30.3)

62 (45.9)

58 (22.2)

 < 0.001

Acute exacerbationa

74 (18.7)

38 (28.1)

36 (13.8)

0.001

 Time interval from diagnosis (months)

34.6 ± 28.2

29.3 ± 20.5

40.2 ± 33.9

0.037

Pneumonia

35 (8.8)

16 (11.9)

19 (7.3)

0.138

Pneumothorax

7 (1.8)

5 (3.7)

2 (0.8)

0.048

Pulmonary hypertension

89 (22.5)

45 (33.3)

44 (16.9)

 < 0.001

Lung cancer

28 (7.1)

14 (10.4)

14 (5.4)

0.065

  1. Data are expressed as mean ± standard deviation or number (%) unless otherwise indicated
  2. aAcute worsening or development of dyspnea < 1 month in duration; new bilateral ground-glass opacity and/or consolidation superimposed on fibrosis; not fully explained by cardiac failure or volume overload
  3. PF progressive fibrosing, ILD interstitial lung disease