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Table 3 Prognostic factors for mortality in patients with fibrosing ILD assessed using a Cox proportional hazards model

From: Progressive fibrosing interstitial lung disease: prevalence and clinical outcome

 

Unadjusted

 

Multivariable

 
 

Hazard Ratio (95% CI)

P-value

Hazard Ratio (95% CI)

P-value

Age

1.069 (1.047–1.091)

 < 0.001

1.075 (1.050–1.100)

 < 0.001

Male

1.312 (0.901–1.909)

0.157

  

BMI

1.025 (0.968–1.086)

0.401

  

Ever-smokers

1.137 (0.780–1.657)

0.506

  

ILD subtype

 

0.078

–

–

iNSIP

1

   

HP

1.874 (0.955–3.678)

0.068

  

RA-ILD

1.325 (0.769–2.281)

0.311

  

SSc-ILD

0.603 (0.250–1.455)

0.260

  

SJS-ILD

1.087 (0.528–2.241)

0.820

  

FVC

0.995 (0.984–1.007)

0.416

  

DLCO

0.989 (0.978–0.999)

0.031

0.982 (0.971–0.993)

0.001

TLC

0.990 (0.977–1.002)

0.108

  

UIP-like pattern

1.642 (1.124–2.399)

0.010

1.458 (0.960–2.212)

0.077

PF-ILD

3.075 (2.107–4.486)

 < 0.001

3.053 (2.066–4.512)

 < 0.001

Steroid ± IM

0.958 (0.484–1.897)

0.902

  
  1. CI confidence interval, PF progressive fibrosing, ILD interstitial lung disease, BMI body mass index, iNSIP idiopathic nonspecific interstitial pneumonia, HP hypersensitivity pneumonitis, RA rheumatoid arthritis, SSc systemic sclerosis, SJS SjÖgren syndrome, FVC forced vital capacity, DLCO diffusing capacity of the lung for carbon monoxide, TLC total lung capacity, UIP usual interstitial pneumonia, IM immunosuppressant
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Respiratory Research

ISSN: 1465-993X

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