Fig. 6
From: Association between particulate matter containing EPFRs and neutrophilic asthma through AhR and Th17
Distinct T-cell populations (characterized in Fig. 3) show dysregulation across immunological pathways essential to eTh17 cell cytokine production. A Upregulated Th17 specific pathways associated with PM exposure in alpha–beta T cells. B Upregulated Th17 specific pathways associated with PM exposure in NK T cells. C Upregulated Th17 specific pathways associated with PM exposure in gamma–delta T cells. Significance was tested by Wilcoxon rank sum test with Bonferroni correction FDR < 0.05. Combined score is a combination of the p-value and z-score (calculated by using a modification to Fisher’s exact test) calculated by multiplying the two scores