Fig. 1From: Dysfunctional lactate metabolism in human alveolar type II cells from idiopathic pulmonary fibrosis lung explant tissueOxidative and glycolytic metabolism in AEC2s from human IPF lungs. A Oxygen-consumption rates (OCR) compared between primary AEC2s from 3 non-fibrotic human lungs (con), AEC2s from 3 IPF transplant patients, and the A549 cell-line. Each AEC2 sample (or A549 cells) were analyzed in quadruplicate replicates. B OCR vs. proton-production rates (PPR) of the same AEC2 cells from A. C Comparisons of PPR/OCR ratios of the AEC2s. All values were normalized to total cellular protein. D Immunocytochemistry of IPF2 AEC2 showing staining for pro-SP-C (FITC or Green) to demonstrate primary cell purityBack to article page