Table 4 Top proteins commonly downregulated in both lung tissue and plasma of IPF patients compared to healthy controls
Gene | Log fold change (lung) | FDR (Lung) | Log fold change (Plasma) | FDR (Plasma) |
|---|---|---|---|---|
IL1RL1 | − 3.544 | 0.000000000105 | − 2.634896607 | 0.0001669 |
IL1R2 | − 3.001 | 0.000000002738 | − 1.033449865 | 0.031564344 |
S100A12 | − 2.829 | 0.000000000327 | − 1.073609496 | 0.044386712 |
IL18R1 | − 2.173 | 0.000000000000 | − 0.722860241 | 0.074670624 |
CD177 | − 1.264 | 0.016722589668 | − 1.261375377 | 0.013794617 |
RETN | − 1.205 | 0.000632239048 | − 1.166268536 | 0.00040745 |
TNNT2 | − 1.012 | 0.000535234220 | − 0.941703387 | 0.035988956 |
FSTL3 | − 0.717 | 0.000055605556 | − 0.89064698 | 0.024740285 |
HIST2H2BE | 0.117 | 0.633132897915 | − 0.630306445 | 0.080621623 |