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Table 4 Top proteins commonly downregulated in both lung tissue and plasma of IPF patients compared to healthy controls

From: Integrated plasma proteomics and lung transcriptomics reveal novel biomarkers in idiopathic pulmonary fibrosis

Gene Log fold change (lung) FDR (Lung) Log fold change (Plasma) FDR (Plasma)
IL1RL1 − 3.544 0.000000000105 − 2.634896607 0.0001669
IL1R2 − 3.001 0.000000002738 − 1.033449865 0.031564344
S100A12 − 2.829 0.000000000327 − 1.073609496 0.044386712
IL18R1 − 2.173 0.000000000000 − 0.722860241 0.074670624
CD177 − 1.264 0.016722589668 − 1.261375377 0.013794617
RETN − 1.205 0.000632239048 − 1.166268536 0.00040745
TNNT2 − 1.012 0.000535234220 − 0.941703387 0.035988956
FSTL3 − 0.717 0.000055605556 − 0.89064698 0.024740285
HIST2H2BE 0.117 0.633132897915 − 0.630306445 0.080621623