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Table 3 Top proteins commonly upregulated in both lung tissue and plasma of IPF patients compared to healthy controls

From: Integrated plasma proteomics and lung transcriptomics reveal novel biomarkers in idiopathic pulmonary fibrosis

Gene Log fold change (lung) FDR (Lung) Log fold change (Plasma) FDR (Plasma)
CCL11 4.484 0.00000000 1.799567355 8.20E−05
CCL22 3.569 0.00000067 0.87049819 0.035988956
CXCL12 2.740 0.00000000 0.943963155 0.006010717
TPSB2 2.449 0.00000002 0.724432917 0.079124595
MDK 2.396 0.00000000 1.272550426 0.035843766
KLK7 2.275 0.00088573 0.842680094 0.02034195
CCL21 2.019 0.00000000 1.40240372 0.000945317
SERPINA5 1.953 0.00010138 0.859861017 0.049974592
FRZB 1.939 0.00000000 1.506003793 0.00103215
GFRA1 1.820 0.00000000 1.307361522 0.048836237
VTN 1.736 0.00000901 0.609196466 0.074839355
CCL5 1.727 0.00000003 1.145110861 0.010668158
CCL3L1 1.654 0.00101204 0.60079124 0.027908725
CXCL9 1.591 0.00458221 1.377906373 0.00483477
RSPO3 1.404 0.00000191 1.729221937 0.0042172
SORCS2 1.247 0.00000009 0.890594785 0.049606009
CCL17 1.163 0.01754183 1.621455261 0.000257494
CTSV 1.129 0.00015761 1.026447098 0.000346371
GZMA 0.992 0.00104687 0.881790954 0.00103215
PDE5A 0.958 0.00000004 0.674159636 0.057080731
A2M 0.839 0.00000012 0.63442842 0.000928021
CTSF 0.737 0.00002812 0.647455699 0.004900564
CHL1 0.717 0.00338922 0.868595763 0.003669314
MSTN 0.677 0.00404260 0.716627957 0.034902232
SPARC 0.631 0.00001012 0.668856674 0.005760412