Table 3 Top proteins commonly upregulated in both lung tissue and plasma of IPF patients compared to healthy controls
Gene | Log fold change (lung) | FDR (Lung) | Log fold change (Plasma) | FDR (Plasma) |
|---|---|---|---|---|
CCL11 | 4.484 | 0.00000000 | 1.799567355 | 8.20E−05 |
CCL22 | 3.569 | 0.00000067 | 0.87049819 | 0.035988956 |
CXCL12 | 2.740 | 0.00000000 | 0.943963155 | 0.006010717 |
TPSB2 | 2.449 | 0.00000002 | 0.724432917 | 0.079124595 |
MDK | 2.396 | 0.00000000 | 1.272550426 | 0.035843766 |
KLK7 | 2.275 | 0.00088573 | 0.842680094 | 0.02034195 |
CCL21 | 2.019 | 0.00000000 | 1.40240372 | 0.000945317 |
SERPINA5 | 1.953 | 0.00010138 | 0.859861017 | 0.049974592 |
FRZB | 1.939 | 0.00000000 | 1.506003793 | 0.00103215 |
GFRA1 | 1.820 | 0.00000000 | 1.307361522 | 0.048836237 |
VTN | 1.736 | 0.00000901 | 0.609196466 | 0.074839355 |
CCL5 | 1.727 | 0.00000003 | 1.145110861 | 0.010668158 |
CCL3L1 | 1.654 | 0.00101204 | 0.60079124 | 0.027908725 |
CXCL9 | 1.591 | 0.00458221 | 1.377906373 | 0.00483477 |
RSPO3 | 1.404 | 0.00000191 | 1.729221937 | 0.0042172 |
SORCS2 | 1.247 | 0.00000009 | 0.890594785 | 0.049606009 |
CCL17 | 1.163 | 0.01754183 | 1.621455261 | 0.000257494 |
CTSV | 1.129 | 0.00015761 | 1.026447098 | 0.000346371 |
GZMA | 0.992 | 0.00104687 | 0.881790954 | 0.00103215 |
PDE5A | 0.958 | 0.00000004 | 0.674159636 | 0.057080731 |
A2M | 0.839 | 0.00000012 | 0.63442842 | 0.000928021 |
CTSF | 0.737 | 0.00002812 | 0.647455699 | 0.004900564 |
CHL1 | 0.717 | 0.00338922 | 0.868595763 | 0.003669314 |
MSTN | 0.677 | 0.00404260 | 0.716627957 | 0.034902232 |
SPARC | 0.631 | 0.00001012 | 0.668856674 | 0.005760412 |