Fig. 3

EBI3 deficiency enhanced the expressions of ECM-associated genes in bleomycin-induced pulmonary fibrosis. A qRT-PCR assay of ECM gene transcripts including Col1a2, Col3a1, lox and Fn1 (n = 5). B mRNA levels of Mmp13, Timp1 which was involved in ECM remodeling and production were measured by qPCR (n = 5). Data are representative of three independent experiments. Data are presented as mean ± SEM. Significance was determined by two-tailed Student’s t test. *P < 0.05, **P < 0.01 and ***P < 0.005