Table 1 Studies characteristics
Study | Country | Study design | Enrolment years | Inclusion criteria | No.RA-ILD/death | Follow-up lengths (years) |
|---|---|---|---|---|---|---|
Wolfe (2007) | Multicentre (US) | Prospective cohort study | 2001–2007 | RA by 1987 ACR criteria; ILD diagnosed by physician and/or hospital records ICD-9 codes | 100/27 | Mean 3 |
Dixon (2010) | Multicentre (UK) | Case–control study | 2001–2008 | RA diagnosed by a physician; ILD diagnosed by physician and/or hospital records ICD-9 codes | 367/84 | Median 3.8 |
Kim (2010) | Multicentre (US) | Case–control study | 2001–2008 | RA by 1987 ACR criteria; ILD diagnosis by HRCT | 82/8 | Median3.9 |
Koduri (2010) | Multicentre (UK) | Prospective cohort study | 1986–1998 | RA by 1987 ACR criteria; ILD diagnosed by clinical, chest X-ray and HRCT finding | 52/39 | Median 10 |
Tsuchiya (2011) | Single-centre (Japan) | Retrospective cohort study | 1996–2006 | RA by 1987 ACR criteria; ILD diagnosed by HRCT finding and/or biopsy | 144/71 | Median 4.5 |
Nakamura (2012) | Single-centre (Japan) | Retrospective cohort study | 1989–2009 | RA by 1987 ACR criteria; Surgical lung biopsy-proven ILD | 54/9 | NA |
Solomon (2013) | Multicentre (US) | Retrospective cohort study | 1977–1999 | RA by 1987 ACR criteria; Surgical lung biopsy-proven ILD | 48/40 | Median 3.7 |
Solomon (2016) | Single-centre (US) | Retrospective cohort study | 1995–2013 | RA diagnosed by rheumatologist ILD diagnosed by HRCT finding | 137/54 | Mean 4.8 |
Zamora-Legoff (2016) | Single-centre (US) | Retrospective cohort study | 1998–2014 | RA by 1987 ACR criteria ILD diagnosed by HRCT finding | 181/72 | Mean 3.1 |
Hozumi (2013) | Single-centre (Japan) | Case–control study | 1995–2012 | RA by 1987 ACR criteria; ILD diagnosed by clinical presentation, pulmonary function tests, HRCT finding and lung biopsy finding | 51/12 | Mean 8.5 |
Yang (2017) | Single-centre (Republic of Korea) | Case–control study | 1991–2011 | RA by 1987 ACR criteria; ILD diagnosed by clinical features and pulmonary function tests, radiographic finding | 77/38 | Mean 10 |
Rojas-Serrano (2017) | Single-centre (Mexico) | Retrospective cohort study | 2004–2015 | RA by 1987 ACR or ACR/EULAR 2010 criteria; ILD diagnosed by HRCT finding | 78/17 | Mean 5.8 |
Jacob (2018) | Multicentre (UK, Republic of Korea) | Retrospective cohort study | 2007–2014 1995–2015 | RA by ACR/EULAR 2010 criteria; RA-ILD diagnosed by multidisciplinary team review | 245/110 | Mean 6.7 |
Song (2013) | Multicentre (Japan) | Case–control study | 1991–2008 | RA by 1987 ACR criteria; UIP diagnosed by ATS/ERS consensus classification for IIP and surgical lung biopsy | 84/10 | Mean 2.75 |
Kelly (2014) | Multicentre (UK) | Case–control study | 1987–2012 | RA by ACR/EULAR 2010 criteria ILD diagnosed by HRCT finding | 230/32 | Mean 14 |
San-Koo (2015) | Single-centre (Republic of Korea) | Retrospective cohort study | 2004–2011 | RA by 1987 ACR criteria; ILD diagnosed by clinical presentation, pulmonary function testing, and radiographic finding | 24/6 | NA |
Nurmi (2018) | Single-centre (Finland) | Retrospective cohort study | 2000–2014 | RA by 1987 ACR criteria; ILD diagnosed by HRCT finding | 60/33 | NA |
Hyldgaard (2019) | Single-centre (Denmark) | Retrospective cohort study | 2004–2016 | RA-ILD diagnosed by physician | 102/38 | Mean 3.8 |
Ito (2019) | Single-centre (Japan) | Retrospective cohort study | 2007–2016 | RA by ACR/EULAR 2010 criteria; ILD diagnosed by symptoms and HRCT finding | 65/16 | Mean 4.7 |
Yamakawa (2019) | Single-centre (Japan) | Retrospective cohort study | 2012–2017 | RA by ACR/EULAR 2010 criteria; ILD diagnosed by a multidisciplinary team | 96/25 | Mean 3.7 |
Kim-2 (2020) | Single-centre (Republic of Korea) | Case–control study | 1995–2015 | RA by ACR/EULAR 2010 criteria; ILD diagnosed by HRCT finding | 153/45 | Mean 4.5 |
Li (2020) | Single-centre (China) | Retrospective cohort study | 2008–2017 | RA by 1987 ACR or ACR/EULAR 2010 criteria; RA-ILD diagnosed by a work group included experienced rheumatologists and radiologists | 278/53 | Median 4.25 |
Wang (2020) | Single-centre (China) | Case–control study | 2016–2019 | RA by ACR/EULAR 2010 criteria; ILD diagnosed by clinical presentation, pulmonary function tests, and HRCT findings | 45/4 | Mean 2.1 |