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Table 1 EC50 values of PG-induced eosinophil shape change were calculated and are given as mean ± standard error of the mean (SEM), n = 2–3

From: Prostaglandin D2 metabolites activate asthmatic patient-derived type 2 innate lymphoid cells and eosinophils via the DP2 receptor

Eosinophil shape change EC50 [nM]

Metabolite

Measured values

Sandig et al. [19]

PGD2

0.7 ± 0.2

0.4

DK-PGD2

2.7 ± 2.3

1.1

∆12-PGD2

1.2 ± 1.8

7.3

15-deoxy-∆12,14-PGD2

1.5 ± 1.6

2.4

9α,11β-PGF2

 > 1000

156.0

PGJ2

1.6 ± 3.8

2.2

∆12-PGJ2

5.6 ± 1.0

3.7

15-deoxy-∆12,14-PGJ2

12.0 ± 0.7

8.4

  1. Published reference values are given in the right column