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Fig. 3 | Respiratory Research

Fig. 3

From: Prostaglandin D2 metabolites activate asthmatic patient-derived type 2 innate lymphoid cells and eosinophils via the DP2 receptor

Fig. 3

A ILC2 migration in the presence of ascending concentrations of PGD2 and selected metabolites, n = 3. Values are given as mean ± SD. Nonlinear curve fit with constraints of bottom constant equal to zero and top constant equal to 100 was applied to derive EC50 and EC70. B Maximal cell migration of PGD2 and selected metabolites. Absolute numbers of migrated cells were compared and normalized to 100% PGD2, n = 7. Values are given as mean ± SD. DK-PGD2: ns, ∆12-PGD2: ns, 15-deoxy-∆12,14-PGD2: p = 0.05, 9α,11β-PGF2: ns, PGJ2: ns, ∆12-PGJ2: p = 0.03 and 15-deoxy-∆12,14-PGJ2: p = 0.01. *p < 0.05

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