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Fig. 1 | Respiratory Research

Fig. 1

From: Circ_PIP5K1A regulates cisplatin resistance and malignant progression in non-small cell lung cancer cells and xenograft murine model via depending on miR-493-5p/ROCK1 axis

Fig. 1

Circ_PIP5K1A was upregulated in DDP-resistant NSCLC tissues and cells. A IC50 of DDP was examined by MTT assay in A549, A549/DDP (A) and H460, H460/DDP (B) cells. C, D the circ_PIP5K1A expression was assayed by RT-qPCR in tumor-resistant tissues (C) and DDP-resistant cells (D). EH total RNA was treated with RNase R (E, F) and cells were incubated with Actinomycin D (G, H), then circ_PIP5K1A and PIP5K1A quantification was conducted by RT-qPCR. **P < 0.01, ***P < 0.001

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