Fig. 4
A MMP-12 activity quantified in lung samples. ELN-PGG-NPs group shows a marked decrease in MMP-12 activity, B Dynamic lung compliance (Cdyn) and C Tidal volume (mm3) values show untreated mice with increased compliance. ELN-PGG-NPs group shows compliance close to that of healthy group (p = 0.07). D Static compliance of mice lungs calculated using pressure–time curves. Untreated mice show mild increase in static compliance. Static compliance of ELN-PGG-NPs treated mice is comparable to that of healthy mice and significantly lower than untreated mice. * p < 0.05 **p < 0.01 ***p < 0.001