Prediction of lung emphysema in COPD by spirometry and clinical symptoms: results from COSYCONET

Respiratory Research

Table 1 Patient characteristics

Variables	Group without CT	Group with CT	p-value
Sex (m/f)	448/292	271/165	0.583
Age (years)	68.0 ± 8.0	66.2 ± 8.2	p < 0.001
BMI (kg/m²)	26.7 ± 5.2	26.7 ± 4.9	0.898
Packyears	46.7 ± 37.6	46.8 ± 36.8	0.950
Smok. never, ex-, act	51/567/121	27/319/90	0.178
FEV₁ %predicted	51.1 ± 18.6	55.4 ± 18.7	p < 0.001
FVC %predicted	76.1 ± 18.9	82.6 ± 20.3	p < 0.001
FEV₁/FVC	0.51 ± 0.11	0.51 ± 0.11	0.475
TLCO %predicted	56.1 ± 22.6	59.6 ± 22.7	0.015
KCO %predicted	64.3 ± 25.6	65.2 ± 21.8	0.531
GOLD grades 1/2/3/4	54/310/283/93	49/211/137/39	0.003
GOLD groups ABCD	237/163/113/222	170/86/80/99	0.014

Comparison of the subgroup with CT scans (study population) and the patients without CT scans from COSYCONET that were participants at the time of the CT scans. Statistical comparisons were performed with either t-tests or Chi-square contingency tables, as appropriate

ISSN: 1465-993X