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Fig. 7 | Respiratory Research

Fig. 7

From: SPECT imaging of pulmonary vascular disease in bleomycin-induced lung fibrosis using a vascular endothelium tracer

Fig. 7

a Reduced AM receptor expression in lung vasculature. Confocal imaging of lung sections from a sham and two bleomycin-treated animals (bleo1 and bleo2) compared to a negative control. RAMP2 receptor activity modifying protein 2. b Reduced expression of AM receptor in humans with IPF. Lung tissue protein expression of the AM receptor (RAMP2) and of other molecular markers in lungs from humans with IPF (n = 11) and control lungs (n = 6). †P < 0.001 vs control. αSMA alpha-smooth muscle actin, IPF idiopathic pulmonary fibrosis, RAMP2 receptor activity modifying protein 2, SM22α smooth muscle protein 22-alpha

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