From: The smell of lung disease: a review of the current status of electronic nose technology
 | Aeonose | BIONOTE | Cyranose 320 | PEN3 | SpiroNose | Tor Vergata |
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Company | The eNose company, Zutphen, the Netherlands | Campus Bio-Medico University, Rome, Italy | Sensigent, California, United States (previously known as: Smith Detections) | Airsense Analytics GmbH, Schwerin, Germany | Breathomix, Leiden, the Netherlands (previously produced by: Comon Invent) | Tor Vergata University, Rome, Italy |
Working Principle (i.e. sensors) | Electrical sensors | Gravimetric sensors | Electrical sensors | Electrical sensors | Electrical sensors | Gravimetric sensors |
Sensing material | MOS | QCM | Conducting polymer | MOS | MOS | QCM |
Array composition | 1 array; 3 sensors | 1 array; 7 sensors operating at 4 different temperatures | 1 array; 32 different polymers | 1 array; 10 different sensors | 4 exhaled breath and 4 reference arrays; 7 different sensors per array | 1 array; 8 sensors |
Breath collection | Tidal breathing straight into eNose | Tidal breathing into Pneumopipe cartridge | Exhalation into sample bag | Exhalation into sample bag | Exhalation straight into eNose | Exhalation into sample bag |
NA | 3Â min tidal breathing | 5Â min tidal breaths, deep inhale, exhalation | 5Â min tidal breathing, deep in- and exhalation | 5 tidal breaths, deep inhale, breath hold, slow exhalation | Deep in- and exhalation | |
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Image source | Rocco et al. 2016 [16] | Tor Vergata University |