Table 6 Efficacy outcomes in the Modified ITT and protocol populations
Outcomes in modified ITT | Steroid + Azithromycin (N = 116) | Azithromycin (N = 110) | Lopinavir/Ritonavir (N = 110) | Total (N = 336) | P value |
|---|---|---|---|---|---|
Death | 4 | 6 | 6 | 16 | Chi2 = 0.67; df = 1; P = 0.71 |
Admission to ICU | 5 | 6 | 7 | 18 | Chi2 = 0.47; df = 1; P = 0.79 |
Intubation declared | 2 | 1 | 3 | 6 | Chi2 = 1.14; df = 1; P = 0.57 |
Outcomes in per-protocol | Steroid + Azithromycin (N = 64) | Azithromycin (N = 51) | Lopinavir/Ritonavir (N = 51) | Total (N = 166) | P value |
|---|---|---|---|---|---|
Death | 2 | 1 | 3 | 6 | Chi2 = 1.20; df = 1; P = 0.55 |
Admission to ICU | 1 | 3 | 4 | 8 | Chi2 = 2.62; df = 1; P = 0.27 |
Intubation declared | 0 | 1 | 2 | 3 | Chi2 = 0.89; df = 1; P = 0.64 |