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Fig. 2 | Respiratory Research

Fig. 2

From: Upregulation of leukocyte immunoglobulin-like receptor B4 on interstitial macrophages in COPD; their possible protective role against emphysema formation

Fig. 2

The correlation of the upregulation of LILRB4 expression on interstitial macrophages with the severity of emphysematous lesions. a Percentages of LILRB4 expression on interstitial macrophages (IMs, left), alveolar macrophages (AMs, middle), and monocytes (right) in the lungs from never-smokers, non-COPD smokers, and COPD patients. n = 21 for never-smokers, n = 16 for non-COPD smokers, n = 14 for COPD patients. Data are presented as median with a dot for each sample. The Steel–Dwass test was used for nonparametric multiple comparisons among the groups. N.S.: not significant. b Correlation analysis of the percentage of LILRB4 positive cells in lung IMs with FEV1/FVC (left), %FEV1 (middle), or %DLCO/VA (right). n = 51 for FEV1/FVC and %FEV1, n = 21 for %DLCO/VA. c Correlation analysis between the percentage of LILRB4 positive cells in lung IMs and Goddard score (left), smoking amount (middle), and age (right). N = 51 for each analysis. To analyze the relationship between variables, the spearman correlation coefficient was used. FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, DLCO diffusing capacity of the lung for carbon monoxide, VA alveolar volume, LAA low attenuation area

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Respiratory Research

ISSN: 1465-993X

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