Smoking induces sex-specific changes in the small airway proteome

Respiratory Research

Table 5 Association between protein levels and number of years since cessation of smoking in former smokers

Protein	Women (N = 24)		Men (N = 22)
Protein	p-value	R-statistic	p-value	R-statistic
Hepatocyte growth factor receptor			0.002	0.64
Interleukin-6 receptor subunit beta			0.002	0.63
Plexin-B2			0.006	0.58
Follistatin-related protein 1			0.009	0.55
Follistatin-related protein 3			0.020	0.50
Inhibin beta A chain			0.030	0.47
Advanced glycosylation end product-specific receptor, soluble			0.035	0.46
Complement decay-accelerating factor			0.038	0.46
Complement C2			0.047	0.44
Antithrombin-III	0.001	0.63
Thyroxine-binding globulin	0.010	0.53
Heparin cofactor 2	0.012	0.52
Complement C3b, inactivated	0.020	0.48
Complement component C9	0.020	0.48
Pigment epithelium-derived factor	0.026	0.46

Only proteins less abundant in current smokers compared to never smokers that significantly increase with time since smoking cessation are shown
p-value and R-statistic are based on linear regression adjusted for age

ISSN: 1465-993X