Table 4 Risk of exacerbation within 180 days as determined by uni- and multivariate cox regression analysis (adjustment for age, gender, oxygen supply, length of hospital stay, COPD grade and treatment group)
Univariate cox regression | Multivariate cox regression | |||
|---|---|---|---|---|
HR (CI 5%, CI 95%) | p-value | HR (CI 5%, CI 95%) | p-value | |
MBL (scaled per 200 ng/mL) | 1.03 (1.00, 1.06) | 0.02 | 1.03 (1.00, 1.06) | 0.048 |
MBL < 500 ng/mL | 0.65 (0.37, 1.15) | 0.14 | 0.56 (0.31, 1.01) | 0.053 |
Ficolin-2 (scaled per 200 ng/mL) | 1.00 (0.99, 1.02) | 0.65 | 1.01 (0.99, 1.03) | 0.42 |
Ficolin-2 < 25% Quantile | 0.82 (0.45, 1.48) | 0.50 | 0.78 (0.43, 1.42) | 0.42 |
IgG deficiency | 1.62 (0.97, 2.71) | 0.07 | 1.42 (0.83, 2.44) | 0.21 |
IgA deficiency | 1.36 (0.43, 4.34) | 0.60 | 1.27 (0.39, 4.19) | 0.69 |
Ig subclasses | ||||
IgG 1 deficiency | 1.69 (1.04, 2.76) | 0.04 | 1.39 (0.82, 2.33) | 0.22 |
IgG 2 deficiency | 2.14 (1.05, 4.33) | 0.04 | 1.98 (0.91, 4.31) | 0.08 |
IgG 3 deficiency | 2.09 (1.09, 4.00) | 0.03 | 1.52 (0.76, 3.05) | 0.23 |
IgG 4 deficiency | 1.24 (0.63, 2.44) | 0.53 | 1.5 (0.69, 3.27) | 0.31 |
IgA 1 deficiency | 1.36 (0.43, 4.34) | 0.6 | 1.27 (0.39, 4.19) | 0.69 |