Effect of prone positioning on oxygenation and static respiratory system compliance in COVID-19 ARDS vs. non-COVID ARDS

Table 1 Patient characteristics

Variables	COVID-19 ARDS	Non-COVID ARDS
Variables	Entire group N = 23	Entire group N = 145	P value^a	PaO₂/FiO₂-matched N = 23	P value^a	Compliance-matched N = 23	P value^a
Age, years	70 (63–74)	67 (59–74)	0.222	75 (70–79)	0.092	66 (60–74)	0.159
Male sex	15 (65.2%)	97 (66.9%)	0.874	17 (73.9%)	0.522	16 (69.6%)	0.753
Height, cm	165 ± 9	163 ± 8	0.374	163 ± 10	0.614	164 ± 8	0.791
Body weight, kg	70 (58–79)	61 (53–70)	0.018	57 (51–69)	0.015	64 (55–69)	0.132
Body mass index, kg/m²	25.6 (22.9–27.4)	22.9 (20.8–26.0)	0.024	22.5 (19.3–24.7)	0.009	22.7 (20.5–27.2)	0.121
Interval between intubation and the first prone positioning session, days	1 (0–2)	2 (1–5)	0.009	1 (0–3)	0.116	2 (1–4)	0.047
Total number of sessions of prone positioning	4 (3–9)	2 (1–4)	< 0.001	2 (1–4)	0.008	2 (1–4)	0.011
Mean duration of prone positioning per session, hours	18 (17–19)	18 (16–19)	0.653	17 (16–18)	0.180	17 (16–20)	0.231
Charlson comorbidity index	4 (3–4)	5 (3–8)	0.012	5 (4–6)	0.011	5 (4–7)	0.032
APACHE II score	20 (12–25)	29 (25–33)	< 0.001	30 (26–35)	< 0.001	29 (25–37)	< 0.001
SAPS II score	42 (31–61)	65 (55–71)	< 0.001	66 (62–78)	< 0.001	65 (58–78)	< 0.001
SOFA score	8 (5–11)	12 (9–14)	< 0.001	12 (9–14)	0.002	13 (11–15)	< 0.001

APACHE acute physiology and chronic health evaluation, ARDS acute respiratory distress syndrome, SAPS Simplified Acute Physiology Score, SOFA sequential organ failure assessment
^aP values are for comparison between patients with COVID-19 ARDS and patients with non-COVID ARDS

ISSN: 1465-993X