Skip to main content

Table 2 Organ involvements of the included sarcoidosis patients according to exposure category

From: Associations between occupational and environmental exposures and organ involvement in sarcoidosis: a retrospective case-case analysis

 

Overall (n = 238)

Exposure

Reactive chemicals (n = 26)

Inorganic dust (n = 74)

Organic dust (n = 63)

Contact with livestock (n = 15)

Close human contact (n = 31)

Admin work only (n = 42)

Active smoker (n = 43)

Organ involvement

 Pulmonary involvement only

164 (69%)

17 (65%)

58 (78%)*

47 (75%)

6 (40%)*

16 (52%)*

27 (64%)

32 (74%)

 Intrathoracic lymph node

235 (99%)

25 (96%)

73 (99%)

63 (100%)

15 (100%)

31 (100%)

40 (95%)§

43 (100%)

 Lung

191 (80%)

22 (85%)

59 (80%)

53 (84%)

11 (73%)

24 (77%)

34 (81%)

38 (88%)

 Liver

23 (9.7%)

1 (3.8%)

3 (4.1%)*

8 (13%)

4 (27%)*

8 (26%)*

4 (9.5%)

3 (7.0%)

 Spleen

37 (16%)

3 (12%)

6 (8.1%)*

7 (11%)

6 (40%)*

10 (32%)*

9 (21%)

4 (9.3%)

 Cardiac

17 (7.1%)

5 (19%)*

3 (4.1%)

2 (3.2%)

4 (27%)*

2 (6.5%)

4 (9.5%)

3 (7.0%)

 Eye

29 (12%)

2 (7.7%)

7 (9.5%)

4 (6.3%)§

0 (0%)

6 (19%)

5 (12%)

11 (26%)*

 Skin (excluding erythema nodosum)

23 (9.7%)

2 (7.7%)

6 (8.1%)

8 (13%)

1 (6.7%)

2 (6.5%)

3 (7.1%)

7 (16%)

 Erythema nodosum

30 (13%)

5 (19%)

11 (15%)

9 (14%)

0 (0%)

3 (9.7%)

5 (12%)

4 (9.3%)

 Neurologic

9 (3.8%)

1 (3.8%)

2 (2.7%)

1 (1.6%)

0 (0%)

2 (6.5%)

1 (2.4%)

2 (4.7%)

 Parotid/salivary gland

8 (3.4%)

0 (0%)

1 (1.4%)

3 (4.8%)

2 (13%)§

2 (6.5%)

2 (4.8%)

0 (0%)

 Bone marrow

9 (3.8%)

0 (0%)

2 (2.7%)

3 (4.8%)

1 (6.7%)

3 (9.7%)§

1 (2.4%)

3 (7.0%)

 Löfgren syndrome

30 (13%)

3 (12%)

9 (12%)

6 (10%)

1 (7%)

3 (10%)

6 (14%)

3 (7%)

  1. Statistics presented: n (%); Statistical tests performed, comparing exposed to non-exposed: Fisher’s exact test or Pearson’s Chi-squared test; * when p < 0.05, §p < 0.10