Table 2 Distributions of family cancer history and lung disease history by status of cases and controls, the corresponding ORs and 95% CIs among non-smokers
Levels of exposure | Cases | Controls | p | OR and 95% CI* |
|---|---|---|---|---|
N (%) (n = 767) | N(%) (n = 767) | |||
Family cancer history | ||||
 Overall cancers | 162 (21.1%) | 169 (22.0%) | 0.185 | 1.189 (0.921, 1.535) |
 Type |  |  |  < 0.001 |  |
  Lung cancer | 20 (2.6%) | 54 (7.0%) |  < 0.001 | 3.347 (1.930, 5.806) |
  Other cancers | 142 (18.5%) | 115 (15.0%) | 0.509 | 0.909 (0.685, 1.206) |
 Relationship |  |  | 0.148 |  |
  First-degree relatives | 133 (17.3%) | 147 (19.2%) | 0.054 | 1.283 (0.995, 1.654) |
  Other relatives | 29 (3.8%) | 22 (2.9%) | 0.880 | 0.958 (0.550, 1.669) |
 Type of cancer and relatives |  |  | 0.002 |  |
  Lung cancer in father, mother or children | 13 (1.7%) | 28 (3.7%) | 0.006 | 2.646 (1.323, 5.291) |
  Lung cancer in siblings | 4 (0.5%) | 20 (2.6%) | 0.001 | 6.329 (2.058, 19.467) |
  Other cancers in father, mother or children | 81 (10.6%) | 73 (9.5%) | 0.767 | 0.948 (0.668, 1.347) |
  Other cancers in siblings | 35 (4.6%) | 26 (3.4%) | 0.558 | 0.850 (0.494, 1.463) |
  Lung cancer in other relatives | 3 (0.4%) | 6 (0.8%) | 0.166 | 2.804 (0.651, 12.0738) |
  Other cancers in other relatives | 26 (3.4%) | 16 (2.1%) | 0.538 | 0.812 (0.417, 1.578) |
Lung disease history | ||||
 Overall lung disease | 44 (5.7%) | 73 (9.5%) | 0.001 | 2.041 (1.356, 3.071) |
 Type |  |  | 0.018 |  |
 Chronic bronchitis | 19 (2.5%) | 23 (3.0%) | 0.203 | 1.523 (0.797, 2.908) |
 Tuberculosis | 10 (1.3%) | 16 (2.1%) | 0.056 | 2.256 (0.980, 5.194) |
 Pneumonia | 8 (1.0%) | 15 (2.0%) | 0.127 | 2.014 (0.820, 4.946) |
 Asthma | 1 (0.8%) | 13 (1.7%) | 0.010 | 14.720 (1.877, 115.449) |
 Other | 6 (0.1%) | 6 (0.8%) | 0.785 | 1.177 (0.365, 3.793) |