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Table 4 Pulmonary function test results and clinical symptoms for two groups of COVID-19 patients with pulmonary fibrosis

From: Pulmonary fibrosis and its related factors in discharged patients with new corona virus pneumonia: a cohort study

 

Group Aa

(N = 33)

Group Bb

(N = 114)

P value

Overall abnormalities ratio in pulmonary function test

54.55% (18/33)

66.67% (76/114)

0.2841

Abnormal lung function ratioc

18.18% (6/33)

22.81% (26/114)

0.7433

Obstructive disorder ratio

6.06% (2/33)

4.39% (5/114)

0.9471

Restrictive disorder ratio

3.03% (1/33)

7.02% (8/114)

0.6679

Small airway disorder ratio

9.09% (3/33)

11.40% (13/114)

0.9535

MEF 25 decreased

36.36% (12/33)

40.35% (46/114)

0.8333

Abnormal lung diffusion function

6.06% (2/33)

7.02% (8/114)

0.8413

The patients with persistent PFT abnormalities and ongoing symptoms

44.44% (8/18)

44.74% (34/76)

0.8094

Severe/critical patients ratio

3.03% (1/33)

24.56% (28/114)

0.0128

Symptomatic patients ratio

30.30% (10/33)

43.86% (50/114)

0.2324

Dyspnea

3.03% (1/33)

1.75% (2/114)

0.8084

exercise limitation

6.06% (2/33)

8.77% (10/114)

0.8887

Cough

18.18% (6/33)

14.91% (17/114)

0.8546

Fatigue

9.09% (3/33)

21.05% (24/114)

0.1910

chest tightness

3.03% (1/33)

7.89% (9/114)

0.5587

Hyposmia

0% (0/33)

1.75% (2/114)

0.9306

Ongoing O2 requirement

0

0

–

  1. Lung function tests were conducted in about 3 months after the onset
  2. aPatients who either had no lung fibrosis, or their lung fibrosis disappeared within 90 days after onset
  3. bPatients who still had lung fibrosis after 90 days from onset
  4. cThe patients were evaluated the lung function using spirometry to obtain relevant indices including first second exhalation volume (FEV1), forced vital capacity (FVC), FEV1/FVC%, forced expiratory flow rate at 50% and 75% of FVC (FEF50%, FEF75%), forced expired flow at 25–75% of FVC (FEF25-75%), inspiratory reserve volume (IRV), tidal volume (TV) and expiratory reserve volume (ERV)
  5. dMEF 25, maximal expiratory flow after 25% of the forced vital capacity has not been exhaled