Fig. 3
Effects of CoQ10 or fish oil supplementation during neonatal IH on the oxidants, hydrogen peroxide (H2O2), 8-isoprostaglandin F2α (8-isoPGF2α), and malondialdehyde (MDA), in lung homogenates on postnatal day 14 (P14) and P21. Pups were exposed to neonatal IH from P0 to P14 during which they were supplemented with CoQ10 or fish oil. Post IH, animals were either euthanized at P14 or placed in RA with no further supplementation for re-oxygenation/recovery until P21. RA control littermates (white bar) remained in RA from birth to P14 or P21. The shaded bars represent groups exposed to 50%/12% O2 IH, and the solid black bars represent groups exposed to 21%/12% O2 IH. Data are expressed as mean ± SEM (n = 6 samples/group)