Fig. 4From: Therapeutic benefits of recombinant alpha1-antitrypsin IgG1 Fc-fusion protein in experimental emphysemaEffects of AAT Fc treatment on elastin immunity and DC function. Spleen MNCs from mice that received elastase were co-cultured with EP and culture supernatants were analyzed for IFNγ or IL-17 production (A). The effects of AAT-Fc or pAAT pre-treatment of bone marrow derived, EP-primed DCs on CD4+ T cell production of IFNγ or IL-17 (B). n = 6 in each group. *p < 0.05 by Tukey–Kramer testBack to article page