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Fig. 1 | Respiratory Research

Fig. 1

From: Family with sequence similarity 13 member A mediates TGF-β1-induced EMT in small airway epithelium of patients with chronic obstructive pulmonary disease

Fig. 1

Expression of family with sequence similarity 13 member A (FAM13A) in small airway epithelium and its correlation with COPD severity and EMT marker expression. The patients were divided into non-smokers without COPD (n = 22), smokers without COPD (n = 23), non-smokers with COPD (n = 10), and smokers with COPD (n = 14) groups. A IHC staining was carried out to detect FAM13A protein expression in the small airway epithelium of the patients. B–D Multivariate Cox proportional hazards analysis, was performed to examine the correlations of FAM13A age as the control variable, expression with pre-bronchodilator FEV1%, PO2, PCO2, and expression of E-cadherin and vimentin. FEV1%pre: pre-bronchodilator forced expiratory volume in 1 s; PO2: partial pressure of oxygen; PCO2: partial pressure of carbon dioxide

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Respiratory Research

ISSN: 1465-993X

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