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Table 2 Kernel targets screened from protein–protein interaction (PPI) network

From: Mechanism of protective effect of xuan-bai-cheng-qi decoction on LPS-induced acute lung injury based on an integrated network pharmacology and RNA-sequencing approach

Gene Closeness centrality Degree Betweenness centrality Topological coefficient
AKT1 0.8615 47 0.2180 0.2200
VEGFA 0.8485 47 0.2348 0.2197
PTEN 0.6747 30 0.0429 0.2842
MTOR 0.6667 30 0.0603 0.2722
HIF1A 0.6588 29 0.0436 0.2861
PIK3CA 0.6222 23 0.0282 0.2988