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Table 1 Baseline clinical characteristics of patients in the Sepsis + ARDS group who were survivors and non-survivors

From: Does an increase in serum FGF21 level predict 28-day mortality of critical patients with sepsis and ARDS?

Parameter Non-survivors
(n = 42)
Survivors
(n = 119)
P value
Age (years) 68 ± 13 65 ± 16 0.137
Gender (male/female) 23/19 84/35 0.062
Coronary heart disease 13 (31.1%) 38 (31.9%) 0.907
Hypertension 12 (28.6%) 36 (30.2%) 0.838
Type 2 diabetes 5 (11.9%) 13 (10.9%) 0.862
Chronic renal failure 3 (7.1%) 8 (6.7%) 0.926
COPD 12 (28.6%) 39 (32.8%) 0.615
Length of stay 10 (2–22) 9 (3–21) 0.578
Mean arterial pressure (mmHg) 68 (35–116) 87 (48–120)  < 0.001
Respiratory rate (per min) 24 (12–40) 22 (13–38) 0.125
Heart rate (bpm) 110 ± 33 98 ± 20 0.022
Temperature (°C) 38.1 ± 1.4 37.2 ± 0.8 0.019
White blood count (109/L) 15.0 ± 6.6 14.3 ± 7.2 0.682
Platelet count (109/L) 131 (17–364) 178 (35–473) 0.055
Hematocrit (%) 31.3 ± 7.0 35.4 ± 5.7 0.050
PaO2/FiO2 (mmHg) 152.1 ± 55.7 164.6 ± 54.5 0.021
Total bilirubin (μmmol/L) 19.5 (4.6–124.7) 19.0 (4.8–98.5) 0.183
Creatinine (μmmol/L) 144.0 (44.9–1477.9) 96.4 (33.7–507.6) 0.009
Lactate (mmol/L) 3.7 (0.9–18.0) 2.7 (1.2–5.6)  < 0.0001
GCS score 9 (3–15) 11 (3–15)  < 0.0001
SOFA score 11 (3–21) 6 (2–18)  < 0.0001
CRP (mg/L) 134.9 (18.6–468.0) 100.7 (9.8–200.0)  < 0.0001
PCT (ng/mL) 16.96 (1.70–200.00) 3.07 (0.15–200.0)  < 0.0001
IL-6 (pg/mL) 367.7 (37.3–498.2) 89.6 (2.9–462.6)  < 0.0001
TNF-α (pg/mL) 63.9 (11.1–215.4) 12.3 (5.8–102.1)  < 0.0001
IL-10 (pg/mL) 597.6 (68.0–798.7) 108.6 (10.7–657.9)  < 0.0001
FGF21 (pg/mL) 3574.7 (327.3–6978.5) 986.6 (32.3–6121.3)  < 0.0001
  1. COPD chronic obstructive pulmonary disease