Skip to main content

Table 1 Clinical characteristics of AECOPD inpatients in the training set and validation set

From: A risk-predictive model for invasive pulmonary aspergillosis in patients with acute exacerbation of chronic obstructive pulmonary disease

 

No. (%)*

 

Characteristic

Training set

(n = 616)

Validation set

(n = 264)

P

IPA

59 (9.6)

24 (9.1)

0.821

Age, years

   

 Mean ± SD

75 ± 10.8

75 ± 10.6

0.936

Gender male

525 (85.2)

222 (84.1)

0.666

Smoking index > 400

113 (18.3)

59 (22.3)

0.170

Comorbidities

   

 Previous tuberculosis

37 (6)

21 (8)

0.286

 Lung cancer

25 (4.1)

17 (6.4)

0.129

 Bronchiectasis

8 (1.3)

7(2.7)

0.163

 Asthma

18 (2.9)

14 (5.3)

0.084

 Lobectomy surgery

13 (2.1)

10 (3.8)

0.153

 Other solid tumor

23 (3.7)

13 (4.9)

0.414

 Hypertension

297 (48.2)

123 (46.6)

0.659

 Diabetes mellitus

94 (15.3)

43 (16.3)

0.700

 Congestive heart failure

119 (19.3)

72 (27.3)

0.009

 Chronic and acute kidney disease

44 (7.1)

15 (5.7)

0.427

 Advanced liver disease

8 (1.3)

1 (0.4)

0.292

 Connective tissue disease

13 (2.1)

7 (2.7)

0.622

Laboratory results

   

 Serum albumin < 30 g/L

151 (24.5)

70 (26.5)

0.530

 GOLD III–IV§

409 (66.4)

177 (67)

0.852

 Respiratory failure

129 (20.9)

74 (28)

0.022

Co-infection

   

 Lung bacterial infection

100 (16.2)

54 (20.5)

0.131

 Pulmonary tuberculosis

12 (19.5)

4 (1.6)

0.788

Previous treatment

   

 Inhale corticosteroids

124 (20.1)

47 (17.8)

0.424

 Oral or intravenous corticosteroids

59 (9.6)

36 (13.6)

0.075

 Cytotoxic drug utility

2 (0.3)

4 (1.5)

0.070

 Broad-spectrum antibiotic > 10 days

45 (7.3)

28 (10.6)

0.104

 Invasive ventilator utility

49 (8)

28 (10.6)

0.202

 ICU admission 1 month prior

54 (8.8)

39 (14.8)

0.008

Hospital acute exacerbation ≥ 2/year

111 (18)

51 (19.3)

0.649

  1. IPA invasive pulmonary aspergillosis, GOLD global initiative for chronic obstructive lung disease, ICU intensive care unit
  2. *Values are presented as numbers and percentages, unless otherwise indicated
  3. This result was obtained from the hospital admission
  4. §The GOLD stage was obtained from the latest pulmonary function test within the last year