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Table 2 Mean baseline FEV1 and lung cancer incidence by sex-stratified quintiles categories of serum urate

From: Serum urate and lung cancer: a cohort study and Mendelian randomization using UK Biobank

Smoking status

Sex stratified quintile of urate*

Number

Mean FEV1 (SD)

Lung cancer events

Person years (× 10,000 PYs)

Lung cancer incidence rate per 10,000 PYs (95%CI)

Overall

1

71,720

2.93 (0.76)

398

50.4

7.9 (7.2–8.7)

 

2

71,895

2.90 (0.77)

366

50.4

7.3 (6.6–8.0)

 

3

71,753

2.87 (0.78)

325

50.6

6.4 (5.8–7.2)

 

4

71,932

2.83 (0.78)

353

50.6

7.0 (6.3–7.7)

 

5

71,952

2.73 (0.79)

482

50.6

9.5 (8.7–10.4)

Never

1

41,109

2.96 (0.75)

48

29.1

1.7 (1.2–2.2)

 

2

40,528

2.94 (0.77)

52

28.6

1.8 (1.4–2.4)

 

3

39,586

2.90 (0.78)

51

28.0

1.8 (1.4–2.4)

 

4

38,387

2.85 (0.78)

56

27.2

2.1 (1.6–2.7)

 

5

35,720

2.76 (0.79)

56

25.2

2.2 (1.7–2.9)

Former

1

21,764

2.92 (0.75)

146

15.2

9.6 (8.2–11.3)

 

2

23,463

2.89 (0.75)

139

16.4

8.5 (7.2–10.0)

 

3

24,993

2.87 (0.76)

142

17.5

8.1 (6.9–9.5)

 

4

26,584

2.82 (0.77)

178

18.6

9.6 (8.3–11.1)

 

5

29,658

2.71 (0.78)

288

20.7

13.9 (12.4–15.6)

Current

1

8623

2.82 (0.82)

204

6.0

34.0 (29.6–39.0)

 

2

7656

2.79 (0.82)

174

5.3

32.8 (28.3–38.0)

 

3

6953

2.77 (0.83)

130

4.9

26.7 (22.5–31.7)

 

4

6727

2.76 (0.84)

118

4.7

25.2 (21.0–30.2)

 

5

6278

2.66 (0.84)

133

4.4

30.3 (25.6–35.9)

  1. *See Table 1 for µmol/L values