Fig. 1

A Heatmap of miRNAs found to be differentially expressed in pediatric survivors and non-survivors of ARDS. The original values were log-transformed. Columns with similar annotations (i.e. male, non-survivors with a pulmonary cause of ARDS or female, non-survivors with non-pulmonary cause of ARDS) were collapsed by taking median inside each group. Both rows and columns are clustered using correlation distance and average linkage. B Quantitative PCR validation of the individual miRNAs by Taqman assays. Eight samples were used for validation—four samples from survivors and four samples from non-survivors. Increased expression of miR-126-3p, miR-191-5p and miR-223-3p and decreased expression of miR-106a-5p, miR-17-5p and miR-29a-5p in the survivors compared the the non-survivors group were similar to the results obtained by Nanostring. *p < 0.05, **p < 0.001