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Table 1 Patients’ characteristics including comparison of patients with or without any treatment limitation (PTL)

From: Patients’ treatment limitations as predictive factor for mortality in COVID-19: results from hospitalized patients of a hotspot region for SARS-CoV-2 infections

Variable All patients (n = 526) No limitation (n = 300) Any limitation (n = 226) p-value
n Median (quartiles) n Median (quartiles) n Median (quartiles)
Demographics/vital parameters
 Sex (%) 526 ♂ 53.4; ♀ 46.6 300 ♂ 55.7; ♀44.3 226 ♂ 50.4; ♀ 49.6 0.252
 Age (years) 526 73 (57; 82) 300 60 (51; 73) 226 81 (76; 87) < 0.001
 Pulse rate (1/min) 523 84 (76; 95) 299 84 (78; 97) 224 82 (73.3; 94) 0.065
 sBP (mmHg) 523 129 (113; 140) 299 130 (115; 140) 224 126 (110; 140) 0.162
 dBP (mmHg) 523 75 (65; 84) 299 77 (70; 85) 224 70 (60; 80) < 0.001
 Body temperature (°C) 525 37.6 (36.8; 38.4) 300 37.7 (37; 38.5) 225 37.4 (36.7; 38.2) 0.007
 SpO2 (%) 506 94 (91; 96) 285 94 (92; 96.3) 220 93 (90; 96) 0.002
Laboratory parameters upon admission
 Hemoglobin (g/dl) 524 13.3 (11.8; 14.6) 300 13.5 (12.2; 14.8) 224 12.9 (11.3; 14.2) < 0.001
 Hematocrit (%) 524 38.6 (34.5; 42.0) 300 39.4 (35.3; 42.3) 224 37.9 (33.3; 41.7) 0.007
 Thrombocytes (G/l) 524 197.5 (150.0; 252.0) 300 198.5 (152.0; 249.8) 224 190 (148.3; 255.8) 0.885
 Leucocytes (G/l) 524 6.5 (4.7; 8.9) 300 6.1 (4.6; 8.4) 224 6.9 (5.0; 9.8) 0.001
 Lymphocytes (G/l) 456 0.9 (0.7; 1.3) 262 1 (0.7; 1.4) 194 0.9 (0.6; 1.3) 0.014
 Neutrophils (G/l) 456 5.1 (3.4; 7.6) 262 4.7 (3.2; 6.8) 194 5.4 (3.8; 8.5) 0.001
 Creatinine (µmol/l) 517 1.1 (0.9; 1.5) 294 1 (0.8; 1.3) 223 1.4 (1.0; 2.0) < 0.001
 eGFR (ml/min) 517 61.1 (37.9; 82.2) 294 73.6 (55.2; 88.1) 223 42.8 (26.3; 62.2) < 0.001
 ALT (U/l) 473 25.0 (17.4; 39.0) 271 28 (19.6; 43.1) 202 21.9 (15.2; 32.5) < 0.001
 GGT (U/l) 448 41.0 (22.3; 79.0) 251 41 (23.0; 75.0) 197 41 (22.0; 92.5) 0.591
 LDH (U/l) 419 311.0 (231.0; 402.0) 238 309 (229.8; 394.8) 181 315 (235.0; 402.5) 0.674
 CRP (mg/dl) 519 6.0 (2.3; 11.5) 297 5.4 (1.9; 10.2) 222 6.5 (3.1; 12.1) 0.014
 IL-6 (pg/ml) 91 66.5 (27.4; 127.0) 55 73.3 (27.7; 127.0) 36 63.6 (24.8; 128.8) 0.858
  1. Bold p-values represent statistical significance (< 0.05)
  2. sBP systolic blood pressure, dBP diastolic blood pressure, SpO2 pulse oxygen saturation, eGFR estimated glomerular filtration rate, ALT alanine aminotransferase, GGT gamma-glutamyl transferase, LDH lactate dehydrogenase, CRP C-reactive protein, IL-6 Interleukin-6