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Table 3 The performance of different thresholds of Tbag/PHA ratio for ATB diagnosis

From: The TBAg/PHA ratio in T-SPOT.TB assay has high prospective value in the diagnosis of active tuberculosis: a multicenter study in China

TBag/PHA threshold

Sensitivity (95%CI)

Specificity (95%CI)

PPV (95%CI)

NPV (95%CI)

PLR (95%CI)

NLR (95%CI)

0.1443

81.7 (79.6–83.6)

86.6 (83.9–89.0)

92.9 (90.9–94.9)

68.8 (66.8–70.8)

6.1 (5.1–7.3)

0.2 (0.2–0.2)

0.1817

76.2 (74.0–78.3)

90.1 (87.6–92.1)

94.3 (92.3–96.3)

63.9 (61.9–65.9)

7.7 (6.1–9.6)

0.3 (0.2–0.3)

0.2004

74.4 (72.1–76.5)

92.3 (90.1–94.1)

95.4 (93.4–97.4)

62.7 (60.7–64.7)

9.6 (7.5–12.4)

0.3 (0.3–0.3)

0.0783

90.1 (88.5–91.5)

67.8 (64.3–71.2)

85.7 (83.7–87.7)

76.1 (74.1–78.1)

2.8 (2.5–3.1)

0.1 (0.1–0.2)