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Table 2 ROC analysis of different indicators in distinguishing ATB from non-TB in suspected patients with positive T-SPOT results

From: The TBAg/PHA ratio in T-SPOT.TB assay has high prospective value in the diagnosis of active tuberculosis: a multicenter study in China

  Cutoff value Sensitivity Specificity PLR P value
ESAT-6 sfc  > 20 76.4 76.0 3.2 P < 0.0001
CFP-10 sfc  > 40 66.4 88.7 5.9 P < 0.0001
PHA sfc  < 214 37.3 85.8 2.6 P < 0.0001
  1. ATB including confirmed ATB and probable ATB
  2. ROC receiver operating characteristic, ATB active tuberculosis, ESAT-6 early secreted antigenic target 6, CFP-10 culture filtrate protein 10, PHA phytohaemagglutinin, sfc spot-forming cells