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Table 3 Patient OCS-dependence comorbidities in OCS-dependent patients.a

From: Mepolizumab improves clinical outcomes in patients with severe asthma and comorbid conditions

Diagnosis description

Patients (N = 544)

Any condition, n (%)

291 (53)

Psychopathologies, n (%)

 

 Any condition

136 (25)

 Anxiety

55 (10)

 Depression

55 (10)

 Mood changes

40 (7)

 Sleep disorders

68 (13)

Osteoporosis/bone fractures, n (%)

 

 Any condition

108 (20)

 Bone fractures

5 (< 1)

 Osteoporosis

107 (20)

Weight gain, n (%)

91 (17)

Adrenal-related, n (%)

 

 Any condition

59 (11)

 Adrenal suppression

18 (3)

 Cushing’s syndrome

20 (4)

 Moon face

41 (8)

Bruising, n (%)

59 (11)

Eye-related, n (%)

 

 Any condition

54 (10)

 Glaucoma

12 (2)

 Cataract

44 (8)

  1. OCS oral corticosteroids
  2. aPatients who had treatment with continuous or near-continuous (at least half of the year) oral corticosteroids