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Table 2 Patient co-morbidities across DREAM, MENSA, SIRIUS, and MUSCA

From: Mepolizumab improves clinical outcomes in patients with severe asthma and comorbid conditions

 

Patients (N = 1878)

Any condition, n (%)

1569 (84)

Upper respiratory, n (%)

 

 Any condition

1102 (59)

 Allergic rhinitis or hay fever

911 (49)

 Sinusitis

288 (15)

 Nasal polyps

293 (16)

Cardiovascular, n (%)

 

 Any condition

620 (33)

  Arrythmia

49 (3)

 Cardiac failure

13 (< 1)

 Cardiomyopathy

4 (< 1)

 Coronary artery disease

48 (3)

 Hypertension

560 (30)

 Hyperglycemia

48 (3)

 Cerebrovascular disorder

7 (< 1)

 Thrombophlebitic event

4 (< 1)

Obesitya, n (%)

603 (32)

Gastroesophageal reflux, n (%)

400 (21)

Psychopathologies, n (%)

 

 Any condition

326 (17)

 Anxiety

141 (8)

 Depression

149 (8)

 Mood changes

78 (4)

 Sleep disorders

158 (8)

Diabetes mellitus, n (%)

148 (8)

Vocal cord dysfunction, n (%)

14 (< 1)

  1. BMI body mass index
  2. aDefined as BMI > 30 kg/m2