Table 1 Baseline characteristics of patients in the full analysis set population
Characteristic | Oxygen group (n = 54) | Hydrogen/oxygen group (n = 53) | P value |
|---|---|---|---|
Age-year, mean(SD) | 69.8 (8.23) | 69.7 (7.72) | 0.959 |
Male sex-n (%) | 46 (85.2%) | 48 (90.6%) | 0.556 |
Height-cm, mean (SD) | 164.7 (6.86) | 167.0 (6.98) | 0.092 |
Weight-kg, mean (SD) | 60.05 (9.86) | 63.52 (12.87) | 0.120 |
BMI-kg/m2,mean (SD) | 22.15 (3.47) | 22.74 (4.09) | 0.421 |
History of Smoking, yes-n (%) | 42 (77.8%) | 45 (84.9%) | 0.667 |
Average smoking amount/day, mean (SD) | 16.4 (8.97) | 24.8 (16.40) | 0.127 |
Disease history, yes-n (%) | 51 (94.4%) | 49 (92.5%) | 0.716 |
Clinical symptoms, yes-n (%) | |||
 Aggravated wheezing | 52 (96.3%) | 48 (90.6%) | 0.270 |
 Increased sputum production | 37 (68.5%) | 35 (66.0%) | 0.838 |
 Sputum purulence | 24 (44.4%) | 21 (39.6%) | 0.696 |
 Fever | 2 (6.9%) | 1 (3.8%) | > 0.999 |
 Aggravated cough | 28 (96.6%) | 24 (92.3%) | 0.598 |
 Increased wheezing rale | 7 (24.1%) | 6 (23.1%) | > 0.999 |
 Increased breathing and heart rate (≥ 20% from baseline) | 0 (0.0%) | 1 (3.8%) | 0.473 |
 Sore throat or rhinorrhea with 5 days | 1 (3.4%) | 0 (0.0%) | > 0.999 |